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butabarbital will reduce the extent or impact of nifedipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.butabarbital will minimize the level or result of aprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.butabarbital will lessen the extent or influence of eltrombopa